Does taking metformin increase the chance of miscarriage?
Miscarriage is common and can occur in any pregnancy for many different reasons. Metformin is not expected to increase the chance for miscarriage. Poorly controlled diabetes in the first trimester of pregnancy can increase the chance of miscarriage.
Does taking metformin increase the chance of birth defects?
Every pregnancy starts out with a 3-5% chance of having a birth defect. This is called the background risk. Use of metformin during pregnancy is not expected to increase the chance of having a baby with a birth defect. Poorly controlled diabetes in the first trimester of pregnancy can increase the chance of having a baby with a birth defect.
Does taking metformin in pregnancy increase the chance of other pregnancy-related problems?
Some studies have suggested individuals with gestational or type II diabetes who were treated with metformin had smaller babies at the time of delivery than those who were treated with insulin. The children exposed to metformin during pregnancy quickly gained weight after birth. Some studies have shown that children exposed to metformin during pregnancy may have a higher chance of having obesity in childhood. However, other studies did not show a difference in obesity in children of individuals who took metformin in pregnancy compared to individuals who did not take metformin or those who took insulin.
Does taking metformin in pregnancy affect future behavior or learning for the child?
Taking metformin during pregnancy is not expected to affect future behavior or learning for the child.
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